Introduction: what is evidence? -- Asking questions -- Finding the evidence -- Assessing baseline risk: prevalence and prognosis -- Assessing diagnostic and screening tests -- Assessing therapy -- Assessing claims of harm or causation -- Assessing systematic reviews and clinical guidelines -- Grading quality of evidence -- Clinical measures -- Assessing quality of life -- Qualitative research -- Complementary and alternative medicine -- Communicating evidence to patients -- Health informatics -- Continuning education -- Using evidence to inform decisions -- The well child -- Universal newborn hearing screening -- Assessment of developmental delay -- Immunizations -- Injury prevention in the clinical setting -- Childhood obesity -- Youth smoking cessation: school-based approaches -- Sudden infant dealth syndrome -- Fever in the young infant -- Fever without focus in the older infant -- Seizures associated with fever -- Meningitis -- Asthma -- Croup -- Bronchiolitis -- Otitis media -- Gastroesophageal reflux in the infant -- Gastroesophageal reflux in the adolescent -- Constipation -- Acute gastroenteritis -- Appendicitis -- Wound repair and tissue adhesives -- Iron deficiency anemia -- Nocturnal enuresis -- Acute urinary tract infection -- Diabetes -- Short stature -- Attention deficit hyperactivity disorder -- Cerebral palsy -- Recurrent apnea in the newborn -- Unconjugated hyperbilirubinemia -- Neonatal encephalopathy -- Pain in the newborn -- Neonatal abstinence syndrome -- Cognitive outcomes in very preterm infants