| 000 | 02431cam a2200397Ii 4500 | ||
|---|---|---|---|
| 999 |
_c6234 _d6234 |
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| 001 | 947816588 | ||
| 003 | OCoLC | ||
| 005 | 20200923065550.0 | ||
| 008 | 160422s2016 enka b 001 0 eng d | ||
| 020 |
_a9780128033098 _q(hd. bd.) |
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| 020 |
_a0128033096 _q(hd. bd.) |
||
| 035 | _a(OCoLC)947816588 | ||
| 040 |
_aBTCTA _beng _erda _cBTCTA _dBDX _dYDX _dOCLCO _dOCLCF _dCOO _dIBI _dOCLCO _dWSU |
||
| 050 | 4 |
_aQH447 _b.G464 2016 |
|
| 060 | 4 | _aQU 460 | |
| 082 | 0 | 4 |
_a576.5 _223 _b1 |
| 100 | _aKOVALCHUK IGOR | ||
| 245 | 0 | 0 |
_aGenome stability : _bfrom virus to human application / _cedited by Igor Kovalchuk, Olga Kovalchuk |
| 264 | 1 |
_aLondon : _bElsevier/Acadmic Press, _c[2016] |
|
| 300 |
_axxii, 690 pages : _billustrations (some color) ; _c29 cm |
||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_aunmediated _bn _2rdamedia |
||
| 338 |
_avolume _bnc _2rdacarrier |
||
| 490 | 1 | _aTranslational epigenetics series | |
| 504 | _aIncludes bibliographical references and index | ||
| 520 | _aGenome Stability: From Virus to Human Application covers the genome stability of DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, with the latter including major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, as well as changes in genome stability in response to aging. Every species has to preserve the integrity of its genome to ensure faithful passage of genetic information to the progeny. At the same time, there are times during the life of the organism and population in general when a fine balance in genome stability and diversification has to be made to benefit the survival of the species. This book teaches the reader how various species maintain this fine balance in genome stability and genome diversification in response to their environments. The book also covers how epigenetic factors contribute to genome stability and how species pass the memory of the encounters to the progeny, thus influencing the genome of the progeny in an indirect manner | ||
| 650 | 0 | _aGenomes | |
| 650 | 0 | _aGenomics | |
| 650 | 0 | _aDNA repair | |
| 650 | 2 | _aGenomics | |
| 700 | 1 |
_aKovalchuk, Igor, _eeditor |
|
| 700 | 1 |
_aKovalchuk, Olga _c(Physician), _eeditor |
|
| 776 | 0 | 8 |
_iOnline version: _tGenome stability : _bfrom virus to human application _w(OCoLC)958580592 |
| 830 | 0 | _aTranslational epigenetics series | |
| 942 |
_2ddc _cBK |
||