000			04294cam a22005174a 4500
999			_c7310 _d7310
001			71223173
003			OCoLC
005			20201005071018.0
008			060824s2007 paua b 001 0 eng
010			_a2006028271
020			_a9780781782104
020			_a0781782104
020			_z2900781782103
024	3		_a9780781782104
035			_a(OCoLC)71223173 _z(OCoLC)493437707 _z(OCoLC)992219047
040			_aDNLM/DLC _beng _cDLC _dNLM _dBAKER _dC#P _dYDXCP _dBTCTA _dLVB _dIG# _dTTS _dDEBBG _dOCLCQ _dOCL _dZWZ _dOCLCQ _dSTJ _dOCLCF _dWUM _dOCLCO _dOCLCQ _dOCLCO _dI8M _dOCLCO _dTHHCU _dXFF _dCNUTO _dVGM _dNJK _dTHHCU _dNJR _dOCLCA _dOCLCQ _dVVL _dFQM _dOCLCQ _dQE2
042			_apcc
050	0	0	_aR853.C55 _bD47 2007
060	0	0	_a2007 A-481
060	1	0	_aWA 950 _bD457 2007
082	0	0	_a610.72 _222
096			_aWA 950 _bD457 2007
100			_aHULLEY, Stephen B.
245	0	0	_aDesigning clinical research / _cStephen B. Hulley, Steven R. Cummings, Warren S. Browner, Deborah G. Grady, Thomas B. Newman.
250			_a3rd ed.
260			_aPhiladelphia, PA : _bLippincott Williams & Wilkins, _c℗♭2007.
300			_axv, 367 pages : _billustrations ; _c26 cm
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
504			_aIncludes bibliographical references and index.
505	0	0	_aGetting started: the anatomy and physiology of clinical research / Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings -- Conceiving the research question / Steven R. Cummings, Warren S. Browner, and Stephen B. Hulley -- Choosing the study subjects: specification, sampling, and recruitment / Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings -- Planning the measurements: precision and accuracy / Stephen B. Hulley, Jeffrey N. Martin, and Steven R. Cummings -- Getting ready to estimate sample size: hypotheses and underlying principles / Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley -- Estimating sample size and power: applications and examples / Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley -- Designing a cohort study / Steven R. Cummings, Thomas B. Newman, and Stephen B. Hulley -- Designing cross-sectional and case-control studies / Thomas B. Newman [and others] -- Enhancing causal inference in observational studies / Thomas B. Newman, Warren S. Browner, and Stephen B. Hulley -- Designing a randomized blinded trial / Steven R. Cummings, Deborah Grady, and Stephen B. Hulley -- Alternative trial designs and implementation issues / Deborah Grady, Steven R. Cummings, and Stephen B. Hulley -- Designing studies of medical tests / Thomas B. Newman [and others] -- Utilizing existing databases / Deborah Grady and Norman Hearst -- Addressing ethical issues / Bernard Lo -- Designing questionnaires and interviews / Steven R. Cummings and Stephen B. Hulley -- Data management / Michael A. Kohn -- Implementing the study and quality control / Deborah Grady and Stephen B. Hulley -- Community and international studies / Norman Hearst and Thomas E. Novotny -- Writing and funding a research proposal / Steven R. Cummings and Stephen B. Hulley.
520			_aProviding a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology, including molecular and genetic clinical research, and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.
600			_2Clinical Research
650		0	_aClinical trials.
650		0	_aMedicine _xResearch _xMethodology.
650		0	_aEpidemiology _xResearch _xMethodology.
650	1	2	_aEpidemiologic Methods.
650	2	2	_aResearch Design.
700	1		_aHulley, Stephen B.
700	1		_aCummings, Steven R., _eauthor.
700	1		_aBrowner, Warren S., _eauthor.
700	1		_aGrady, Deborah, _eauthor.
700	1		_aNewman, Thomas B., _eauthor.
942			_2ddc _cBK